TWO CASES OF GASTROINTESTINAL STROMAL TUMOR (GIST) OF THE DUODENUM

Abstract

Two cases of gastrointestinal stromal tumor (GIST) of the duodenum are reported.
Patient 1, a 75-year-old woman referred to the hospital because of right lateral abdominal oppressive sensation, was found having a segmental torous lesion without mucosal change in the trasitional area from descending to horizontal portion of the duodenum on duodenography and upper gastrointestinal endoscopy. After considering findings of CT, magnetic resonance imaging, and angiography, surgery was performed with a diagnosis of non-epithelial tumor (questionable GIST). During surgery there was no hepatic metastasis, peritoneal dissemination, or lymph node involvement. The removed tumor was 11×11×8cm in dimension.
Patient 2, a 58-year-old man, was referred to the hospital because of an abnormality on upper gastrointestinal series at a medical checkup. Close exploration disclosed an about 3-cm sized protruding tumor with smooth margin in the duodenal lumen at the horizontal portion of the duldenum. With a diagnosis of non-epithelial tumor (questionable GIST), the patient was operated on.
In the two cases, a local excision of the duodenum was carried out. Pathological diagnosis was duodenal GIST, uncommitted type. Case lwas diagnosed as malignant and Case 2 was diagnosed as benign GIST of the duodenum.