REGRESSION OF MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) LYMPHOMA OF THE RECTUM AFTER ERADICATION OF HELICOBACTER -REPORT OF A CASE-

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma of the colon and rectum is extremely rare. We present a case of MALT lymphoma of the rectum that regressed after eradiation of Helicobacter pyloli (H.P.). A 52-year-old woman complaining of anal bleeding was admitted to the hospital with a suspicion of MALT lymphoma. Colonoscopic examination revealed an ulcerative lesion with bleeding in the dentate line and rectum (Rb). Pathological examination showed diffuse infiltration of atypical lymphocytes, which were positive for CD79 α immunostaining and also formed lymphoepithelial lesions, and confirmed the diagnosis of B-cell type MALT lymphoma. Under the enough informed consent, eradication therapy for H.P. was successfully carried out. Colonoscopic examination showed marked regression of the rectal tumor. Almost complete regression was further confirmed by a colonoscopy 6-months after the treatment.