Abstract
A 48-year-old man undergone a total gastrectomy for gastric leiomyosarcoma and histlogically diagnosed as low grade malignant tumor 7 years before was admitted to the hospital because of an abdominal tumor. As a result of various examinations, a large metastatic liver tumor occupying the entire left lobe was diagnosed, and a left lobectomy of the liver was performed on September 12, 2000. Histological examination revealed that the degree of malignancy in the metastatic site was higher than that in the original site. Multiple liver matastases in the residual liver appeared 3 months after the operation. Despite hepatic arterial infusion chemotherapy, he died 13 months after the operation.
There have been 28 cases of gastric leiomyosarcoma with hepatectomized liver metastasis in the Japanese literature. This is rare case because the metastic liver tumor could be resected after a long time 7 years, had elapsed following the initial operation. This case also suggests that there is a possibility of liver metastasis of gastric leiomyosarcoma even if the primary trmor is small and diagnosed as low grade malignancy, so that long-term observation is necessary.