Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
A CASE OF NEUROENDOCRINE CELL CARCINOMA
Yoshiko YANOYoshiichi MAEURAKeiji YAMAZAKIShigeyuki HOJOWakio ENDOShigeru OKAMOTO
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2003 Volume 64 Issue 2 Pages 352-355

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Abstract

A 76-year-old man admitted June 18, 2001, for epigastric pain was found in gastrography and gastroendoscopic examination to have a Borrmann 3 tumor occupying the gastric antrum up to the middle of the stomach. Biopsy examination suggested a preoperative diagnosis of poorly differentiated gastric adenocarcinoma. Computed tomography (CT) showed regional lymph node metastasis, but no liver metastasis. We conducted distal gastrectomy with regional lymph node dissection on Jnly 3. Tumor cells in the resected specimen stained positively in Grimelius, chromogranin A, and NSE staining. The tumor was diagnosed as gastric neuroendocrine cell carcinoma. Although the prognosis of this disease is very poor, the patient remains alive and recurrence-free 1 year and 3 months after surgery.

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