Abstract
We reported a case of a 48-year-old man with fibrolamellar hepatocellular carcinoma (FLHCC), which is rare in Japan. The patient was referred to us due to hepatic tumor which was found with liver dysfunction at a medical checkup. HBs-antigen and HCV-antibody were negatie. Both the serum AFP and the PIVKA-II were elevated. The tumor was about 4cm in diameter in the posterior segment of liver on ultrasonograpy (US). Abdominal plain CT scan showed a low-density tumor, and dynamic CT showed a heterogeneous enhancement with gradual enhancement from the peripheral region. Angiography revealed hypovascularity. Ultrasound-guided fine needle biopsy confirmed the presence of FLHCC, and right hepatectomy was performed. FLHCC is an uncommon variant of HCC occurring in young and usually non-cirrhotic livers, and has a better prognosis than other hepatocellular carcinomas.
