Abstract
We report two cases of endocrine cell carcinoma that originated from the breast, a very rare phenomenon.
Patient 1, a 32-year-old woman, was seen at the hospital because of a right breast tumor. Aspiration biopsy revealed class III cytology, and the tumor was resected to make a histological diagnosis.
Patient 2, a 67-year-old woman, was seen at the hospital because of a left breast tumor. Aspiration biopsy cytology suggested an endocrine cell carcinoma, and a modified mastectomy was carried out.
Hematoxylin and eosin staining, chromogranin A staining, and electron-microscopic examination led to a diagnosis of endocrine cell carcinoma originating from the breast in both cases.