Abstract
We describe a case of multiple jejunal gastrointestinal stromal tumors (GIST) accompanied with von Recklinghausen's disease. A 63-year-old man presented with melena at a local clinic and was referred to our hospital for further evaluation because of anemia. Upper gastrointestinal series and abdominal CT scans revealed a jejunal tumor. Surgery was performed for the tumor in October, 2004. An outside protruding lesion of 5.5cm in diameter at the beginning of the jejunum was confirmed, and a smaller jejunal mass was also found near the lesion. Resection of partial jejunum was done for the main tumor, and wedge resection of jejunum was performed for the smaller one. Histopathological findings revealed a fascicular proliferation of spindle-shaped cells in the tumors. Immunohistochemical findings demonstrated that both tumors' cells were positive for c-kit, CD34 and S-100, and negative for SMA. The pathological diagnosis was multiple GIST, since both tumors were located between the submucosa and subserosa. There are no signs of recurrence to date.
