Abstract
A very rare variant of benign monoclonal gammopathy found in a 70-year-old male patient with silicosis was presented.
Immunoelectrophoretic studies on his serum disclosed the presence of two paraproteins in γ-globulin area both of which proved to be IgG and type L. After the purified M-components were reduced, alkylated and then decomposed, they were subjected to disc electrophoresis. The results showed that each of the two paraproteins proved to be homogenous immunoglobulin and have light chain different in mobility on electrophoresis, respectively.
The problem, whether the paraproteins here reported were derived from one clone or two different clones, remains unsolved.
