Abstract
It has been reported that hemopexin (Hx) is a β1-glycoprotein with high affinity for heme and its serum level is reduced in certain patients such as hereditary spherocytosis, sickle cell anemia, hemorrhagic pancreatitis and thalassemia major, correlated with the degree of intravascular hemolysis or more specifically the plasma heme pigment level.
Recently, we had two clinical cases of the transient hypohemopexinemia after surgical procedures. Case one was 67 year old man with aneurysm of left common iliac artery who undertook the reconstructive operation under blood transfusion of 5250 ml. Case two was 35 year old woman with primary aldosteronism who was treated by the left adrenectomy.
From the various investigations, these results were obtained. 1) The transient hypohemopexinemia may follow the surgical procedures. 2) This may appear in the patient with profound ahaptnglobinemia. 3) This may relate to the excessive hemolysis. 4) This may occur due to the consumption of Hx.
