Abstract
130 cases of leukemia with tumor formation including our own 5, except chloroma, which were reported in Japan from 1953 to 1973, were summerized to discuss their clinical manifestation, treatment and prognosis.
The results were as follows.
1) The incidence of tumor formation was frequent in bone including bone marrow, mediastinum, skin and kidney.
2) In acute leukemia tumor appeared most frequently in its initial stage but recently the incidence increased in the remission stage according to the progress of chemotherapy.
3) In chronic myelogenous leukemia tumor formation suggests acute exacervation.
4) On the treatment to tumor better results were obtained in acute lymphatic leukemia, but poor results in chronic myelogenous leukemia.
5) In our 5 cases combination chemotherapy with Neocarzinostatin was proved to be excellent for tumors.
6) In the treatment to tumor extirpation should be performed for localized tumor. Irradiation is considered to be one of the effective method. Chemotherapy is less effective, but combination chemotherapy including Neocarzinostatin is more effective therapy.
