Abstract
1. The medical records of 71 cases of malignant lymphoma examined at the Department of Hematology, Nagasaki Univercity School of Medicine during the 3-year-period from April 1972 to May 1975 were reviewed for data on serum calcium, phosphorus and white blood cell count. High serum calcium level were found in 20 cases. Of these 13 patients (7 cases of reticulum cell sarcoma and 6 cases of lymphosarcoma) were of leukemic type, more than 20% of white blood cells being abnormal. All the 13 patients died within 6 months after hospitalization.
2. Five autopsied cases of leukemic malignant lymphomas with hypercalcemia are described. They all died in 40 to 180 days after hospitalization. At autopsy 4 cases were diagnosed as reticulum cell sarcoma and one as lymphosarcoma. Electron microscopic findings of the tumor cells in the blood of lymphosarcoma apparently revealed characteristics of lymphatic cells, while those of reticulum cell sarcoma failed to show findings enough to elucidate the origin of the cells, although they were different from lymphatic cells. There were no fine structures in these cells to suggest parathormone excretion.
