Abstract
In malignant lymphoma eosinophilia is not necessarily rare. We observed that it occurred at any stage, and in about 20-30% of cases during the whole course. Eosinophilia in Hodgkin's disease, though frequently mentioned, was less often found than in lymphosarcoma. And various lesions of the skin were observed in about 20% of cases of maligdant lymphoma with eosinophilia. In Hodgkin's disease and lymphosarcoma, males were more frequently accompanied with eosinophilia than females. An interesting feature was the fact that the age-specific incidence curves for malignant lymphoma with eosinophilia were bimodal, in spite of a rather lower proportion of malignant lymphoma under the age of 40 years. The immune deficiency was not so severe in malignant lymphoma with eosinophilia, and eosinophilia per se did not appear to carry a prognosis different from that for malignant lymphoma itself. Immunological aspects of eosinophilia in malignant lymphoma are discussed from the observation of cutaneous lesions, cellular immunity and serum IgE level.
