Abstract
There have been only a few reports on leukemia in married couples. Recently we encountered two couples with acute leukemia: the first couple was a husband with acute promyelocytic leukemia and his wife, still living, with acute monocytic leukemia, and the other a husband with acute monocytic leukemia and his wife with acute lymphocytic leukemia, who died 3.5 years prior to the onset of the disease of her husband.
At present it is very difficult to determine whether or not simultaneous occurrence of leukemia in couples is more than the chance. The accumulation of data of such cases will throw a light on the study of epidemiology of leukemia.