Abstract
A 52-year-old man was admitted to the Hospital on December 8, 1972, because of albuminuria and edema in the legs and scrotum.
Physical examination revealed bilateral pleural effusions and generalized edema, without lymphadenopathy or hepatosplenomegaly.
Blood examination disclosed no anemia, a slight leukocytosis with lymphocytosis, and an infiltration of 85.5% small lymphocytes in the bone marrow.
Serum protein analysis showed monoclonal hyperglobulinemia (IgG, subclass 3, κ type).
In the earlier stage, administration of corticosteroid was effective in reducing pleural effusion but not in the later stage. He died of acute pericarditis on February 11, 1974, after repeated pleural paracenteses. Postmortem examination revealed, no swelling of any lymphatic tissue, no hepatosplenomegaly, but an increase of subcutaneous and mesenterial fatt tissues contained with lymphocytic infiltration and amyloid deposition.
Systematic infiltration of lymphocyte and amyloid deposition in fatt tissues in C. L. L. (medullary form) were reviewed.
