Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
A Case of Hypoplastic Anemia Presumably Caused by Chlorpromazine
H. KOBASHII. MIYOSHII. KIMURAJ. SAKATOS. SAINOH. SUWAKIS. OTSUKI
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Keywords: chlorpromazine
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1979 Volume 20 Issue 11 Pages 1492-1496

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Abstract
Hypoplastic anemia in a 39-year-old woman probably caused by chlorpromazine is reported. The patient visited a hospital because of fever and petechiae in July, 1976. For 13 years, she had been treated with chlorpromazine, trifluoperazine and levomepromazine for schizophrenia. The initial blood study revealed Hb 4.6g/dl, RBC 160×104/mm3, Ht 13%, WBC 1,200/mm3 and platelet count 1.7×104/mm3. The sternal bone marrow was hypoplastic with 74.2% lymphocytes. The patient was given transfusion of blood and platelets and treated with prednisolone and oxymetholone. About 3 months later, the hematologic finding gradually improved and a remission was obtained in May, 1977.
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© 1979 The Japanese Society of Clinical Hematology
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