Abstract
A 59-year-old woman was admitted to our hospital because of fever in September, 1975. A diagnosis of typical acute leukemia was made and the complete remission was easily obtained by anti-leukemic therapy. In May, 1976, however, she was readmitted because of relapse. In spite of several courses of re-induction therapy remission was not obtained again and a severe granulocytopenia continued. In January, 1977, sepsis was complicated and high fever persisted in spite of the combined administration of antibiotics. In February, sdinal paralysis developed suddenly and she died of respiratory distress. Autopsy revealed multiple fungal infections, i.e., candidiasis in the spleen and kidneys, mucormycosis in the liver, mucormycosis and aspergillosis in the lungs. Mucormycotic thrombosis in many dura-arachnoidal vessels caused the spinal cord softening.
