Abstract
The effect of granulocyte transfusions on septicemia in pasients with acute leukemia was evaluated by comparing 23 patients receiving only antibiotics therapy with 7 patients receiving both antibiotics therapy and granulocyte transfusions. Only 26% of patients treated with antibiotics therapy (3 drug combination; cephalosporin+broadacting penicillin+aminoglucoside) survived from septicemia, while 85.7% of patients treated with both antibiotics therapy and granulocyte transfusions survived from septicemia. This indicates that granulocyte transfusions enhance survival in patients with septicemia occured in granulocytopenic periods of acute leukemia.
