Abstract
A fifty-year-old male was admitted with a chief complaint of cervical lymphadenopathy in January 24, 1979. He noticed fever up to 38°C and swelling of the tonsils and cervical lymph nodes in February 1978 and visited a university hospital, where a biopsy of a tonsil was done. Pathological diagnosis was non-specific tonsillitis and oral administration of antibiotics resulted a diminution of the lymphadenopathy but fever continued. 60Co irradiation 42 times was applied to the both mandibular and cervical regions with beneficial results. In September 1978 lymph node swelling reappeared on axillar, inguinal and cervical regions and the pathological diagnosis of the biopsied inguinal lymph node was immunoblastic lymphadenopathy. 60Co irradiation was applied five times to the thoracic, abdominal and both inguinal regions.
On admission marked lymph node enlargement, up to 4 cm. in diameter, was observed on cervical, axillar and inguinal regions. There was no hepato-and splenomegaly. Pathological diagnosis of the left axillar lymph node biopsy material was immunoblastic sarcoma. Study of the lymphocyte subpopulation of the lymph node biopsy material revealed a decrease in E rosette and an increase in IgGλ positive cells on the cell surface. After BACOP therapy fever and lymph node swelling subsided but a complicated interstitial pneumonitis led to the death.
