Abstract
There is increasing evidence that certain hereditary abnormality of coagulation systems and fibrinolytic system result in a predisposition to thromboembolism.
These abnormalities include antithrombin III deficiincy, dysfibrinogenemia and molecular abnormality of plasminogen. However all these affected members have not had thrombotic problems, and it is reasonable to assume that another thrombogenic risk factor such as age, trauma, operation, infection, pregnancy, hyperestrogenemia, varix or hyperlipidemia might be involved.
In this presentation, these aspects together with the author's studies on hereditary molecular abnormality of plasminogen in a patient with recurrent thrombosis were discussed.
