Abstract
Two cases of T cell type tumor were reported. Case 1: A 54-year-old male was admitted to Nihon University Hospital because of general lymphadenopathy. From the histological examination of the left supraclavicular lymph node biopsy specimen, a diagnosis of malignant lymphoma (large lymphoid type) was made. The roentgenogram demonstrated a solid tumor with ulcer creator im the stomach. The diagnosis of malignant lymphoma was established by gastroscopic biopsies and cytologic study. In the examination of surface markers, E rosette forming cells were 26% in peripheral blood and 42% in lymph node cells, EAC rosette forming cells were 42% in peripheral blood and 58% in lymph node cells. These results suggested that tumor cells were of T cell origin with C3 receptor. Case 2: A 72-year-old male was admitted to the hospital because of general lymphadenopathy and leukocytosis. On admission, tumor cells reached 69.5% of the leukocytes in the peripheral blood and 30.8% of the nucleated cells in the bone marrow. In the examination of suface markers, E rosette forming cells were 38% in peripheral blood and 59% in lymph node cells, EAC rosette forming cells were 8% in peripheral blood and 40.5% in lymph node cells. By acid phosphotase staining, a coarse granule was observed in the cytoplasm. Skin involvement was present. He was an inhabitant of Nagasaki district. These findings were considered to be similar in many respects to “adult T cell leukemia” described by Takatsuki et al.
