1981 Volume 22 Issue 10 Pages 1525-1530
We studied the safty of blood component extraction procedure with continuous-flow cell separator (IBM 2997) for normal donors. The changes of CBC and blood chemistry before and after blood component extraction were investigated.
1) The significant decrease of WBC, hemoglobin and hematocrit was seen in the leucocyte extraction group.
2) The significant decrease of platelets and WBC was seen in the platelet extraction group.
3) Indirect bilirubin, serum protein, albumin, calcium and inorganic phosphate decreased significantly after the procedure. Other liver and kidney function tests showed decreased values, because of dilution due to blood expansion by infusion of physiologic saline.
4) In three cases among 34 donors mild citrate adverse reaction were noted.
In conclusion, blood component extraction procedure with IBM 2997 is considerd a safe method for donors.