Abstract
A 29-year-old man was admitted to our hospital because of dyspnea and fever. Physical examination showed pyoderma in face. Lymph nodes were not palpable and hepatosplenomegaly was not noticed.
Laboratory findings revealed pancytopenia and hypofunction of celluar immunity in immunological studies. Bone marrow study observed hypocellular that 22 percent consisted of reticulum cells which had characteristics of PAS (±) peroxidase (-), acid phosphatase (+) and tartrate resistant (+).
He was treated a number of antibiotics and blood transfusions but vigorous treatments failure to save his life and he died due to respiratory infection about eleven months after onset. The autopsy was performed, it showed hemosiderosis due to frequent blood transfution and reticulum cell proliferation with erythrophagia in the spleen, bone marrow and liver. Histological diagnosis was reactive reticulosis.
The systematic classification of reticulosis was formulated by Kojima and Rappaport, but there are still controversial problems. In this paper we reported that our case followed on fatal course despite reactive reticulosis histologically, and reticulosis was discussed.
