Abstract
Acute lymphocytic leukemia (ALL) was classified into 7 subtypes according to the analysis of surface markers of leukemic cells of 37 patients with acute lymphocytic leukemia in Formasa. These subtypes included T, B, and null cell types and types originated from their precursors at different identifiable stages of maturation of lymphocytes, such as Ia-type, cALL-type, pre B-type, and defective B-type. T-ALL was less frequent in Formasa than in Japan and other western countries. The prognostic value of this classification and its relevance to the clinical manefestation of acute lymphocytic leukemia were investigated. In general, this classification was proved to have relationship to clinical status. For example, T-and B-ALL were resistent to chemotherapy and showed unfaborable prognosis, and pre B-ALL occurred in adults, sensitive to the treatment, however, relapsed easily.
