Abstract
A case of acute myelomonocytic leukemia with segmented neutrophil containing Auer bodies is reported. A 30 year-old male patient was admitted to the Keio University Hospital complaining of malaise and eruptions on the fingers and soles for three weeks. On admission, the white blood cell coumt was 8,200/cmm with 9% neutrophils, 29% monocytes, 23% blast cells and 1% promyelocytes. The leukocyte alkaline phosphatase score was very low. A bone marrow aspirate revealed replacement of the normal hematopoietic cells by blast cells. A diagnosis of acute myelomonocytic leukemia was made on the basis of the cytochemical findings of leukemic cells. Several Auer bodies were observed in the cytoplasm of some blasts and segmented neutrophils in the peripheral blood and bone marrow. On electromicroscopic study, mature segmentad neutrophils containing Auer bodies had no specific granules. These observations emphasized the leukemic origin of these cells.
