Abstract
Hemolytic jaundice complicating infectious mononucleosis occurred in a 14-year-old girl with hereditary elliptocytosis. She had no history of hemolysis. Negative direct Coombs' test and negative cold antibody of anti-i specificity did not suggest the autoimmune hemolysis. She recovered spontaneously. Electrophoresis of hemoglobin and Heinz body formation test were normal, and twenty-two kinds of enzymes of red cells were within normal limits, but slightly increased osmotic fragility in twenty-four hour incubated blood.
Members of this family, totalling fifty-three through four generations, were evaluated, and elliptocytes were found in six of them. None of these elliptic members had any history and any evidence of hemolysis.