Abstract
The patient was a 13-year-old boy who had hepatomegaly, an abdominal mass, ascites, and paresthesia in the left thigh. A diagnosis of Burkitt's lymphoma was made after biopsy of the abdominal mass. After conventional chemotherapies, the patient received high doses of BCNU, cyclophosphamide, BH-AC, and 6-MP, followed by infusion of cryopreserved autologous bone marrow cells. Hematological recovery occurred 21 days after the transplantation, and the tumor was once thought to be eradicated. However, 73 days after the transplantation, lymphoma relapsed with leukemic manifestations. CNS involvement developed thereafter, and the patient died 140 days after the transplantation. Autopsy revealed the dissemination of lymphoma cells especially in the bone marrow, optic nerves, and prostate.
