A Case of Autoimmune Hemolytic Anemia Associated with Ovarian Dermoid Cyst

Abstract

Autoimmune hemolytic anemia (AIHA) associated with ovarian dermoid cyst is presented. A 40-year-old woman was admitted because of anemia and jaundice in August, 1981. Normocytic normochromic anemia with reticulocytosis and hypercellular bone marrow with marked erythroid hyperplasia was observed. LDH_1,2 and indirect bilirubin were elevated and serum haptoglobin level was low. Direct Coombs' test was positive. The patient was diagnosed as warm type AIHA. The IgG was assinged anti-e specificity. Ovarian dermoid cyst was found by body CT. Although prednisolone were effective moderately, anemia was markedly improved after removal of the ovarian dermoid cyst. The positive Coombs' test turned to be negative 3 months after operation. No significant antibody against the patient's RBC was detected both in the cyst fluid and in the supernatant of the cultured cells from the cyst.