1985 Volume 26 Issue 4 Pages 549-554
This report presents a case of 28-year-old woman who suffered from thrombotic thrombocytopenic purpura (TTP) with typical findings including severe hemolytic anemia, thrombocytopenic purpura, moderate proteinuria and hemiparesis in the 14th week of her first pregnancy.
She progressively became comatose with convulsions in spite of treatment with methylprednisolone, aspirin and FOY, but completely recovered on plasma exchange and plasma infusion followed by artificial abortion.
However, she continued to suffer from relapses, manifested by thrombocytopenia, which were observed with the menstrual cycle in spite of oral administration of aspirin and dipyridamole. Relapses of TTP could be successfully controlled by plasma infusion, but not by immunoglobulin infusion.
