Abstract
A mediastinal castleman lymphoma was found in a 29-year-old female associated with microangiopathic hemolytic anemia (MHA). Systemic manifestation and laboratory findings of trancient neurological sign, fever, proteinuria, thrombocytopenia and MHA suggested thrombotic thrombocytopenic purpura (TTP). Histologically, the proliferation of capillaries and mature lymphocytes were seen within the tumor and the formation of numerous thrombus was disclosed in the capsular vessels.
The hematological abnormalities were normalized by the administration of prednisolone. No reccurence of hemolysis has been observed after the removal of the tumor. This is the first case report of castleman lymphoma of hyaline vascular type associated with MHA or TTP.
