Abstract
A 64-year-old male was diagnosed as erythroleukemia in January, 1985. Abnormal chromosomes observed in his bone marrow cells were del (1)(p22), del(3)(p14p25), 2t(1;21)(p22;p11), 3del(7)(q22), dicentric (dic), various-sized rings and minutes, -5, -20, PCD (premature centromere division), endoreduplication, 4n etc. The proportion of cells with copies of t(1;21) and del(7)(q) were high when erythroblast cells increased. After DCMP-therapy, althogh the proportion of blast cells were decreased, those with abnormal karyotypes were not so much decreased. Among cells with abnormal karyotypes those with dic were decreased and those with rings and minutes were increased. Dic may have been changed to rings and minutes due to the effect of chemotherapy.
