A Case of Primary Malignant Lymphoma of the Prostate

Abstract

A 55-year-old male noticed forceless urination and pollakisuria in summer of 1984. He visited the urological department of Kagawa Medical School in Sep. '85, because his symptoms were getting worse. Urological examinations revealed signs compatible with “benign prostatic hypertrophy” and a transurethral resection of the prostate was performed. The histological examination of the resected specimen revealed “malignant lymphoma, diffuse, small cell type”. His clinical stage was IIB prostate (+) according to the Ann Arbor classification. He was referred to our medical department for systemic chemotherapy. The combination chemotherapy with COPP (cyclophosphamide, vincristine, procarbazine and prednisolone) was started immediately, followed by five courses with no evidence of recurrence.
The occurrence of primary lymphoma of the prostate is rare, less than 1% of prostatic malignancies. Eight cases have been previously reported in Japan, but most of them were found at the far advanced stage with poor prognosis. This is the ninth case, fortunately found at a very early stage.