Primary B Cell Lymphoma of the Skull Following Head Trauma; A Case Report
1987 Volume 28 Issue 4 Pages 589-593
Details
1987 Volume 28 Issue 4 Pages 589-593
A 65-year-old woman was admitted to our hospital because of a forehead mass appearing at a site of previous trauma. Pathological examination of the mass revealed diffuse lymphoma, mixed cell type (LSG classification). There was no sign of lymphadenopathy. Her WBC was 6,500/μl with no abnormal lymphocytes. Gallium-scan showed high activity only at the forehead. Head-CT showed a contrast-enhanced large soft tissue mass on both sides of the bone with very little change of the bone itself. Abdominal-CT and lymphangiography revealed no evidence of systemic lymphoma.
She was treated with irradiation (5,000R) to the soft tissue mass on both sides of the bone. Resolution of the mass was successfully obtained. After completion of irradiation therapy right periauricular and axillary lymphadenopathy developed, and multiple areas of high activity was observed in the abdomen by gallium-scan. Spinal fluid was normal in appearance. Right periauricular lymph node biopsy revealed diffuse lymphoma, mixed cell type. Immunological phenotyping of the neoplastic lymphocytes revealed Ig G-k.
The patient achieved complete remission after administration of vincristine, Endoxan, and Adriacin. After consolidation by identical schedule, complete remission has been maintained up to the time of writing (12+ months).
