Abstract
T lymphocyte colony formation (T-CFU) of patients with non-Hodgkin's lymphoma (mainly aleukemic) were examined by methylcellulose one-step method. T-CFU of untreated patients were 41.2±61.2/5×104 cells compared with 192.0±94.3/5×104 cells of normal subjects. T-CFU of B cell type lymphoma were markedly depressed (22.0±26.0/5×104 cells), whereas T-CFU of T cell type lymphoma were nearly normal range (125.3±73.4/5×104 cells). After achievement of complete remission by chemotherapy, T-CFU tends to recover. On the other hand, after radiation therapy T-CFU were markedly depressed and the depression continued over 6 months.
