6. 多孔性再生セルロース膜(BMM)中空糸による血漿蛋白質の濾過

奥山 堅司; 福島 誉子; 三浦 泰裕; 本間 玲子; 真鍋 征一; 石川 元; 佐谷 満州夫; 小室 勝利

doi:10.11406/rinketsu.29.662

Function Analysis of Human Plasma Proteins Passed Through the Microporous Regenerated Cellolose Membrane (BMM) Hollow Fiber

Kenji OKUYAMA, Yoshiko FUKUSHIMA, Yasuhiro MIURA, Reiko HONMA, Sei-ichi MANABE, Gen ISHIKAWA, Masuo SATANI, Katsutoshi KOMURO

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Keywords: microporus regenerated cellulose membrane hollow fiber, plasma proteins, infectious viruses

JOURNAL RESTRICTED ACCESS

1988 Volume 29 Issue 5 Pages 662-665

DOI https://doi.org/10.11406/rinketsu.29.662

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Abstract

Functions and physicochemical properties of human plasma proteins prepared by filtration through the microporus regenerated cellulose membrane (BMM) hollow fibers were tests.
Factor-VIII, Factor-IX, antithrombin-III, Fibrinogen and complement activities were not decreased after passed through these membranes having their mean pore size larger than 20 nanometer.
Physicochemical properties were also maintaned.
ATLV, HIV, HBV and non-A, non-B hepatitis viruses may be eliminated from human plasma using these membranes.
This filtration methods are quite useful to get a virus free plasma or blood products.

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