Erythrocyte Membrane-protein Anomaly in March Hemoglobinuria

Abstract

The erythrocyte membrane protein in a 54-year-old patient with march hemoglobinuria was examined by SDS-PAGE and no evidence of aberrant erythrocyte membrane components was found.
Since Banga discribed first in 1979, three reports were published and five patients with march hemoglobinuria were studied of erythrocyte membrane protein by SDS-PAGE. Comparison of these cases with ours reveals that the age of four cases with erythrocyte membrane protein anomaly ranges from 16 to 31 years old (mean 23 years old), while two cases without anomaly was seen in 43 and 53 years of age respectively. From these findings, it's susceptible that march hemoglobinuria with erythrocyte membrane protein anomaly occurs predominantly in younger patients and without anomaly occurs in elder patients.