Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
Factors Related to Prognosis and Relapse in Acute Myelomonocytic and Monocytic Leukemias (M4 and M5)
Atsuko KOYAMA, Chikashi SHIRAKAWA, Hideyuki MASAKI, Fusanari HORIUCHI, Hiroyuki HAMAZAKI, Takuya FUJIMOTO, Kiyohiro IRIMAJIRI, Atsushi HORIUCHI
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Keywords: acute myelomonocytic leukemia, acute monocytic leukemia, number of monocytes, relapse
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1990 Volume 31 Issue 11 Pages 1787-1793

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Abstract
To analyse the factors which were related to prognosis at first examination and early diagnosis of relapse in complete remission phase, 26 patients with acute myelomonocytic leukemia (M4) and acute monocytic leukemia (M5) were investigated.
There was a tight relationship between age and remission rate in patients with M4 and M5. Six of M4 with eosinophilia (M4Eo) patients revealed 83.3% as remission rate with good prognosis in the survival curve. LDH level of them was lower than other patients singnificantly. In order to diagnose relapse before clinical manifestations, it was useful to follow up number of mature monocytes (over 600/μl) in the peripheral blood.
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© 1990 The Japanese Society of Hematology
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