Rinsho Ketsueki
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
Malignant Lymphoma with Acute Renal Failure and Nephrotic Syndrome
Mieko MATSUIMiwako MATSUZAKIYoshinori SHIMAMOTOMutsumi SHIGYOMasako UCHIDAKazutosi ONOMasayuki SANOTakanobu SAKEMIMasaya YAMAGUCHI
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1990 Volume 31 Issue 2 Pages 229-233

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Abstract
A case of non-Hodgkin's lymphoma with nephrotic syndrome and acute renal failure is described.
A 60-year-old Japanese male was admitted to our hospital in November, 1988, because of lymphadenopathy, fever, night sweat, weight loss. On physical examination, lymphadenopathy was present in both cervical, submandibular, supraclavicular, axillar and inguinal regions. The leukocyte count was 9,700/μl with 85% neutrophils and 2% atypical lymphocytes. Renal function was normal. Lymph node biopsy showed non-Hodgkin's lymphoma of diffuse, large cell type. Immunohistologic examination showed T cell type.
A few days later, he fell into acute renal failure. After systemic chemotherapy, he showed prompt improvement in renal function. Echo and computerized tomography (CT) of abdomen revealed no compression of the ureters and bladder. Renal biopsy findings suggested mesangium proliferlative glomerulonephritis without invasion of tumor cells.
Our case seemed to be rare and was compared with previous reports.
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© 1990 The Japanese Society of Hematology
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