1997 Volume 38 Issue 9 Pages 788-791
We report here with a 46-year-old man with refractory multiple myeloma receiving allogeneic peripheral blood stem cell transplantation from his HLA-matched brother. The preparative regimen consisted of TBI (12Gy), VP16 (15mg/kg) and cyclophosphamide (120mg/kg). GVHD prophylaxis consisted of cyclosporin A and short course of methotrexate. The donor received G-CSF at 10μg/kg/day for 5 consecutive days and underwent leukapheresis on days 5 and 6. The neutrophil recovery to 500/μl and platelet recovery to 20,000/μl were day 12 and day 15, respectively. The patient is currently well with no GVHD or graft failure and a complete donor's chimerism.
