Actinomycetologica
Online ISSN : 1881-6371
Print ISSN : 0914-5818
ISSN-L : 0914-5818
Review Articles
Engineering Actinomycetes Genes to Make Known and New Drugs
C. Richard Hutchinson
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2002 Volume 16 Issue 2 Pages 48-53

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Abstract

Three applications of engineered polyketide synthase genes are reviewed in which the erythromycin and FK506 genes were used to make novel antibacterial and neuroregenerative drugs. Heterologous expression of the genes for industrial production of antibacterial and anticancer drugs is also featured.

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© 2002 The Society for Actinomycetes Japan
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