2024 Volume 76 Issue 1 Pages 69-78
Myxoinflammatory fibroblastic sarcoma (MIFS) is a slow-growing sarcoma with most occurring in the distal extremities of middle-aged adults. We report here a case of MIFS occurred in the vulva of a woman in her 60s. The patient was referred to our hospital because of a vulvar mass that had gradually increased in size with pain, over the past five years. A solid mass less than five cm was observed on the right temporal side of the clitoris. A benign soft tissue tumor was suspected on contrast-enhanced MRI.Vulvar tumorectomy was performed to confirm the diagnosis, and the histopathological diagnosis was MIFS. The surgical margin was positive, so we planned to resect the remaining tumor additionally. The remaining mass was resected along with the clitoris, and reconstructive surgery was performed using a genital femoral flap for the vulvar defect. The histopathological diagnosis was MIFS as in the initial surgery. In this case, no local recurrence or distant metastasis was observed 18 months after the reoperation. A high local recurrence rate, and late recurrence of MIFS has been reported. Although rare, lymph node metastasis and lung metastasis have also been reported. Long-term and strict follow-up, including imaging studies is necessary. 〔Adv Obdtet Gynecol, 76(1): 69-78, 2024(R6.2)〕
