Analysis of Protein Fractions of Cerebrospinal Fluid by Means of Disc-electrophoresis (Polyacrylamide-Gel Electrophoresis)

Part 2. Protein Fractions of normal Cerebrospinal Fluid

Abstract

Fractionation of normal cerebrospinal fluid proteins was carried out by Disc-electrophoresis and the obtained patterns were compared with those of normal sera.
Protein fractions of cerebrospinal fluid were named provisionally as follows:
Prealbumin (ρ), albumin (A), α_L-fraction, α₁'-and α₂'-fraction, transferrin (Tr), β₂'-fraction, βγ-fraction, and S_α2-fraction. The mean value (17 cases) of relative concentration of each protein fraction in normal cerebrospinal fluid was as follows; ρ: 4.0%, A: 73.7%, α_L: 2.1%, α₁'-α₂': 3.8%, Tr: 5.8%, β₂': 3.0%, βγ: 5.6%, S_α2: 2.0%.