Abstract
We could obtain the chiken by artificial fertilization from the hen (White Leghorn) having hemagglutination-inhibition antibody induced by natural infection of Japanese encephalitis. And the rates of disappearance of maternal antibody in chickens were examined.
The results obtained were as follows.
1) Linearity of the semilogarithmic plots of antibody titer in the chicken against the time was proved.
2) Hemagglutination-inhibition titer of maternal antibody at the time of hatch as obtained by extrapolation was about 1:600. The value was the same as that of maternal hen.
3) A half life of hemagglutination-inhibition antibody in the chicken was proved to be 4 days.
4) Hemagglutination-inhibition antibody in the chicken was proved to exist mainly in γ-globulin fraction by starch block electrophoresis.
5) From the above results we must take chicken into consideration as an amplifier of Japanese encephalitis virus.
