Abstract
The purpose of this study is to evaluate hemostatic effect of the mouthwash containing tranexamic acid (TR) which is known as a hemostatic and antiinflammatory drug.
The hemostatic effect was studied by the modification of bleeding method with the peritoneum of a rat on the three kinds of test solution; mouthwash containing TR, blank solution (mouthwash without TR) and control (purified water).
The following results were obtained;
1) Hemostatic effect of the mouthwash containing TR could be evaluated by the modification of bleedind method with the peritoneum of a rat.
2) It was recognized that hemostatic effect of the mouthwash containing TR was remarkably stronger than control at 30min. after administrations.
3) The blank solution showed anti-hemostatic effect, which was presumably due to the effect of the ingredients contained in the solution, such as surface active agents, perfumes, antiseptic agents and so on.
