Abstract
Generally, women recognize aging with the appearance of wrinkles at the corner of the eyes or around the mouth. Thus one of the essential aims of cosmetics is the development of substances for wrinkle repair. In the process of developing cosmetics for this purpose, it is essential to establish a highly reproducible method for determining wrinkle depth. Several methods exist for this purpose, which include 3-dimensional analysis by laser light, image analysis, and conventional scoring. All of these methods use image analysis to determine wrinkle depth. However, each of these methods produce different results depending upon the way the image is obtained and the type of analysis used. We thus tried to establish a new evaluation method which uses image analysis in combination with a standard scale. This study shows that our method is highly reproducible and was very suitable on evaluation of the wrinkle depth.