Surgical Case Reports
Online ISSN : 2198-7793
Case Report
A Case of Ascending Colon Perivascular Epithelioid Cell Tumor Presenting with Intestinal Intussusception: Case Report
Mitsuki YokotaHidekazu Takahashi Hiromi TsujiYuka IwamiJuavi Jitjan WatsapolShohei TakaichiMasakatsu PakuKazuya IwamotoTomofumi OhashiYujiro NakaharaTadafumi AsaokaChu MatsudaKazuhiro NishikawaIchiro TakemasaTakeshi Omori
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2025 Volume 11 Issue 1 Article ID: cr.24-0090

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Abstract

INTRODUCTION: Perivascular epithelioid cell tumors (PEComas) arising from the colon are uncommon. This case report describes a 40-year-old woman who presented with lower abdominal pain and was subsequently diagnosed with a colonic PEComa causing intestinal intussusception.

CASE PRESENTATION: The patient initially presented with lower right abdominal pain. Computed tomography revealed an intestinal mass in the ileocecal region, prompting surgical intervention. Due to the nature of the mass, endoscopic repair was not feasible, and she underwent an emergency laparoscopic ileocecal resection. A significant mass was identified in the ascending colon, comprising proliferating spindle-shaped cells within the colonic wall. Immunohistological analysis revealed positive staining for smooth muscle actin (+), HMB-45 (+), and MelanA (±), confirming the diagnosis of PEComa. The patient recovered uneventfully and was discharged on postoperative day 7.

CONCLUSIONS: Colonic PEComa is a rare malignancy. This case adds to the existing knowledge regarding intestinal intussusception caused by colonic PEComa.

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© 2025 The Author(s). Published by Japan Surgical Society
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