2025 Volume 11 Issue 1 Article ID: cr.25-0184
INTRODUCTION: Intussusception in adults is a rare condition, and gastric cancer prolapsing into the duodenum is an even rarer phenomenon. We present a case of early gastric cancer originating in the gastric body with duodenal intussusception and discuss the clinical considerations based on the patient’s overall condition and existing literature.
CASE PRESENTATION: A 69-year-old man with a 30-mm tumor arising from the posterior wall of the gastric body was scheduled for elective surgery. During hospitalization for diabetes mellitus management, he developed sudden epigastric pain and nausea. Upper gastrointestinal endoscopy revealed tumor prolapse into the duodenum, leading to a diagnosis of ball valve syndrome. After successful endoscopic reduction, open local gastrectomy was performed. Pathological examination confirmed a well-differentiated tubular adenocarcinoma, classified as pT1b (SM2) N0M0, pStage IA.
CONCLUSIONS: Gastric cancer with duodenal intussusception is often early-stage and characterized by well-differentiated tubular adenocarcinoma. Depending on the patient’s condition, endoscopic resection or limited surgical resection may be viable treatment options for this rare condition.
