2002 Volume 30 Issue 2 Pages 97-100
One aim of this prospective multicenter trial was to determine whether bypass surgery can prevent stroke recurrence in patients with major cerebral artery occlusive diseases and hemodynamic cerebral ischemia determined by quantitative measurement of cerebral blood flow. The other aim was to determine whether improvement in hemodynamic cerebral ischemia by bypass surgery can prevent the progression of neuropsychological disorders or improve neuropsychological function. The subjects were 128 patients who had been enrolled in the study for 27 months from November 1st 1999 to January 30, 2001. Each patient underwent treatment according to the study program, and the 2-year follow-up survey of the patients is now under way. Of 128 patients enrolled in the study, 66 were assigned the medically treated group and 62 to the surgically treated group. Nine patients in the medically treated group and 2 in the surgically treated group reached endpoint. The incidence of stroke recurrence did not differ significantly between the two groups (p=0.0577). The entry to the study will end in March 2002 and the final results will come out in 2004.
