Abstract
The aim of this study was to elucidate the incidence of a depressive state at a mean followup of 22 years in patients with moyamoya disease. Furthermore, this study examined the possibility of frontal lobe dysfunction influencing the occurrence of depressive state. Thirty patients were assessed using the Zung Self-rating Depression Scale, the Quick Inventory of Depressive Symptomatology-J, and the Frontal Assessment Battery in an outpatient setting. Eight patients (26.7%) were found to have developed a depressive state. Frontal lobe function, disease duration, and headache were statistically related to the occurrence of a depressive state. Further studies are needed to clarify the correlation between a depressive state and frontal lobe dysfunction; however, patients with moyamoya disease should be evaluated and treated as needed for a depressive state.
