Abstract
We studied Xenon-CT cerebral blood flow (CBF) after local thrombolysis with urokinase. Nine patients (5 males and 4 females) were analyzed. Occluded arteries were middle cerebral artery in 7 cases, internal cerebral artery in 1 case and basilar artery in 1 case. CBF decreased not only in the infarcted area but also in a wide area of the affected hemisphere. CBF of the non-affected hemisphere also decreased although the degree was less than on the affected side. CBF of the chronic phase in 4 cases tended to increase in the non-affected hemisphere, but it decreased in the affected hemisphere. From the symptomatic viewpoint, neurological deficits such as hemiparesis, aphasia, consciousness disturbance remained in 8 cases. Many obstacles must be resolved for the functional recovery of such patients.