Abstract
Male adult rats were fed standard laboratory chow (C) or 32% sucrose solution plus standard laboratory chow (S) for 4 to 5 weeks. S caused an increase in caloric intake, but the increase in body weight did not differ between C and S. S exhibited an improved cold tolerance and an enhanced nonshivering thermogenesis (NST) . This enhanced NST was associated with increased brown adipose tissue size and increased plasma insulin level.
From these results it is concluded that sucrose overfeeding could provoke a cross-adaptive effect to cold, probably by potentiating NST in brown adipose tissue.
